Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain
نویسندگان
چکیده
منابع مشابه
Structural Basis of the Chromodomain of Cbx3 Bound to Methylated Peptides from Histone H1 and G9a
BACKGROUND HP1 proteins are highly conserved heterochromatin proteins, which have been identified to be structural adapters assembling a variety of macromolecular complexes involved in regulation of gene expression, chromatin remodeling and heterochromatin formation. Much evidence shows that HP1 proteins interact with numerous proteins including methylated histones, histone methyltransferases a...
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چکیده ندارد.
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BACKGROUND M-phase phosphoprotein 8 (MPP8) was initially identified to be a component of the RanBPM-containing large protein complex, and has recently been shown to bind to methylated H3K9 both in vivo and in vitro. MPP8 binding to methylated H3K9 is suggested to recruit the H3K9 methyltransferases GLP and ESET, and DNA methyltransferase 3A to the promoter of the E-cadherin gene, mediating the ...
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ژورنال
عنوان ژورنال: Nature Structural & Molecular Biology
سال: 2010
ISSN: 1545-9993,1545-9985
DOI: 10.1038/nsmb.1856